| Parichy Lab |
Images: salamanders
|
Salamander development, genetics, and genomics |
In addition to zebrafish and their relatives, the lab maintains an interest in salamander pigment pattern development and collaborates on studies of salamander genetics and genomics. |
embryos |
![]() |
Shown are embryos of Taricha torosa (upper) and Ambystoma tigrinum (lower) at the tailbud stages. Because of their large size (~5 mm), salamander embryos are ideal for experimental manipulation. |
larvae |
![]() |
Larvae of three species of Ambystoma that differ in pigment pattern. These patterns are especially distinctive at the hatching stage seen here, when larvae are especially vulnerable to predators. |
axolotls |
![]() |
Axolotls, Ambystoma mexicanum, do not undergo metamorphosis and instead remain in a permanently aquatic, paedomorphic state. Shown is a wild-type adult as well as a white mutant adult that completely lacks pigment cells due to an early defect in neural crest development. |
Ambystoma tigrinum |
![]() |
This species exhibits an early pigment pattern in aquatic larvae consisting of a light horizontal stripe in the middle of the flank and vertical bars of melanocytes over the dorsal flank. Subsequently, the larvae metamorphose and develop a terrestrial adult pigment pattern of bright spots on a dark background. |
Taricha torosa |
![]() |
This species exhibits horizontal melanophore stripes at early larval stages and a uniform brown pattern as a terrestrial adult. Experimental analyses reveal evolutionarily derived patterning mechanisms, as compared to other salamander species. |
Ambystoma species |
![]() |
Terrestrial adults of six species of Ambystoma exhibiting a variety of pigment patterns including rings, speckling, longitudinal stripes and irregular spots. |