Parichy Lab
Images: mutants

 

Selected Parichy lab zebrafish mutants for adult pigment pattern and post-embryonic neural crest lineages

 

line

whole fish

detail

 

description

movies

refs

wild-type

 
dark stripes of melanophores with light interstripe regions of yellow xanthophores; iridescent iridophores throughout
movies

1, 2

albino
  unmelanized melanophores; widely available mutant    
bonaparte
 
reduced melanophores, xanthophores, and iridophores; name reflects small size and residual patch of iridophores on chest
braque
  disrupted stripes, peripheral nervous system defects    
cezanne
 
fewer melanophores and defective iridophores
chagall
 
disrupted pattern
da vinci
 
fewer melanophores
dali
 
fewer stripes; semi-dominant
dali/+
 
fewer melanophores, spots
degas
 
disrupted pattern; severely runted
duchamp
    fewer, dispersed melanophores; severe fin defect; severely runted  
3
duchamp/+
 
spots, fewer melanophers; short fins; semi-dominant
ednrb1
   
stripes and spots; fewer melanophores and iridophores; ednrb1 encodes a G protein-coupled heptahelical receptor
 

4

fms
 

disrupted stripes fewer melanophores; xanthophores absent; fms encodes a receptor tyrosine kinase (Csf1r)

movies
3, 5, 6
kit
 
fewer melanophores; kit encodes a receptor tyrosine kinase
 

5, 7

nadia1545
  nearly unmelanized melanophores, lighter xanthophore pigmentation; from natural population    
oberon
 
lightly pigmented or absent melanophores; temperature-sensitive
picasso
 
fewer adult melanophores; glial and peripheral nervous system defects
8
 
fewer adult melanophores; cataracts; fin bone defects
puma
 
fewer adult melanophores; glial and peripheral nervous system defects

8, 9, 10

renoir
 
disrupted stripes; fewer melanophores and xanthophores
seurat
 
small spots